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--- en:giuseppe-de-donno [2023/03/25 21:22] – omnipedia
+++ en:giuseppe-de-donno [2023/09/06 19:28] (current) – omnipedia
@@ Line 24: / Line 24: @@
 He didn't understand why there wasn't a commitment on the part of everyone to support and spread this approach as widely as possible, which could save so many lives.
-He was unable to comprehend when Italian public institutions promoted a study on hyperimmune plasma therapy by identifying Pisa as the leader for the elaboration of the treatment protocol, which did not have an experience equal to his on this, instead of Mantua or Pavia, where it had already been a much wider experimentation was carried out and with favorable results. [2] The study concluded in April 2021 that no benefits had been found, leaving De Donno even more embittered. [3] He had not been asked to contribute to the definition of the therapeutic protocol to be applied, therefore nothing in reality could be said about the validity of the De Donno treatment protocol, but then precisely that study was used in Italy to discourage the diffusion of therapy based on hyperimmune plasma. There is ample documentation of the fact that instead the De Donno protocol, correctly applied, was bringing excellent results.
+He was unable to comprehend when Italian public institutions promoted a study on hyperimmune plasma therapy by identifying Pisa as the leader for the elaboration of the treatment protocol, which did not have an experience equal to his on this, instead of Mantua or Pavia, where it had already been a much wider experimentation was carried out and with favorable results.
+[(DeDonnoRef30>>
+title: Plasma therapy reduced deaths by 15 to 6%
+url: https://www.dottnet.it/articolo/30847/la-terapia-col-plasma-ha-ridotto-i-decessi-dal-15-al-6-/
+)]
+[(DeDonnoRef40>>
+title: Coronavirus, De Donno in the Senate: "Politics wants to silence science" (14.05.2020)
+url: https://www.youtube.com/watch?v=nVIq1Bqk3Wg
+)]
+The study concluded in April 2021 that no benefits had been found, leaving De Donno even more embittered.
+[(DeDonnoRef50>>
+title: COVID-19: tsunami study, plasma does not reduce risk of respiratory worsening or death
+url: https://www.iss.it/primo-piano/-/asset_publisher/3f4alMwzN1Z7/content/covid-19-studio-tsunami-il-plasma-non-riduce-il-rischio-di-peggioramento-respiratorio-o-morte
+)]
+He had not been asked to contribute to the definition of the therapeutic protocol to be applied, therefore nothing in reality could be said about the validity of the De Donno treatment protocol, but then precisely that study was used in Italy to discourage the diffusion of therapy based on hyperimmune plasma. There is ample documentation of the fact that instead the De Donno protocol, correctly applied, was bringing excellent results.
+[(DeDonnoRef60>>
+title: "Me pregnant recovered from Covid: plasma therapy saved me and my daughter"
+url: https://www.youtube.com/watch?v=ZBJKmsIWYgM&t=636s
+)]
+[(DeDonnoRef70>>
+title: Convalescent plasma for coronavirus disease 2019 in pregnancy: a case report and review
+url: https://www.ajogmfm.org/article/S2589-9333(20)30118-X/fulltext
+)]
+[(DeDonnoRef80>>
+title: Mortality reduction in 46 severe Covid-19 patients treated with hyperimmune plasma. A proof of concept single arm multicenter trial
+url: https://haematologica.org/article/view/9826
+)]
+[(DeDonnoRef90>>
+title: Safety and Efficacy of Convalescent Plasma in Elderly COVID-19 Patients: The RESCUE Trial
+url: https://www.mcpiqojournal.org/article/S2542-4548(21)00029-1/fulltext
+)]
+[(DeDonnoRef100>>
+title: Early and persistent viral clearance in COVID-19 patients treated with convalescent plasma
+url: https://www.sciencedirect.com/science/article/pii/S1246782021000641?via%3Dihub
+)]
-De Donno continued to be surrounded by the affection of the many patients he had effectively healed with his treatments and by thousands of admirers throughout Italy, but his life ended tragically on July 27, 2021, perhaps because of the weight of what the doctor had unjustly suffered up to that time.
+In the Wikipedia article on De Donno, a work of censorship seems to have been carried out, in which both the reference to the scientific study in which he had participated and the subsequent ones that had highlighted the usefulness of the therapy he had proposed were removed. Therefore, it seems that the act of ostracism against him is continuing.
-After his death, other studies followed which showed that there are treatment protocols based on hyper-immune plasma that have proven effective in the treatment of Sars-CoV 2, as De Donno had already verified, working tirelessly in the ward.
+In any case De Donno continued to be surrounded by the affection of the many patients he had effectively healed with his treatments and by thousands of admirers throughout Italy, but his life ended tragically on July 27, 2021, perhaps because of the weight of what the doctor had unjustly suffered up to that time.
+After his death, other studies
+[(DeDonnoRef110>>
+title: COVID-19 Convalescent Plasma for the Treatment of Immunocompromised Patients: A Systematic Review and Meta-analysis
+url: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2800275
+)]
+[(DeDonnoRef120>>
+title: Early Outpatient Treatment for Covid-19 with Convalescent Plasma
+url: https://www.nejm.org/doi/full/10.1056/NEJMoa2119657
+)]
+followed which showed that there are treatment protocols based on hyper-immune plasma that have proven effective in the treatment of [[Sars-CoV-2]], as De Donno had already verified, working tirelessly in the ward.
 His greatest dream is that an ethical research center could be born between Mantua and Modena, also connected with many other universities. It would be nice if a study center of this type could bear his name in the future.